Beneficial role of naringin, a flavanoid on nickel induced nephrotoxicity in rats.

  title={Beneficial role of naringin, a flavanoid on nickel induced nephrotoxicity in rats.},
  author={Kasinathan Amudha and Leelevinothan Pari},
  journal={Chemico-biological interactions},
  volume={193 1},
This study was conducted to investigate the beneficial role of naringin on nickel induced nephrotoxicity. Nickel (Ni) (20mg/kg body weight (b.w.) was administered intraperitoneally (i.p.) for 20 days. Naringin was administered orally (20, 40 and 80 mg/kg b.w.) with i.p. administration of Ni. Ni administration increased the levels of serum urea, uric acid and creatinine with a significant decrease in creatinine clearance and decreased levels of urea, uric acid and creatinine in urine. The levels… CONTINUE READING
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