Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes.

@article{Ye2015BeneficialMA,
  title={Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes.},
  author={Jianping Ye},
  journal={Frontiers of medicine},
  year={2015},
  volume={9 2},
  pages={139-45}
}
In obesity, chronic inflammation is believed to induce insulin resistance and impairs adipose tissue function. Although this view is supported by a large body of literature, it has been challenged by growing evidence that pro-inflammatory cytokines may favor insulin sensitivity through induction of energy expenditure. In this review article, interleukin 15 (IL-15) is used as a new example to explain the beneficial effects of the proinflammatory cytokines. IL-15 is secreted by multiple types of… CONTINUE READING
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Inflammation during obesity is not all bad: evidence from animal and human studies.

American journal of physiology. Endocrinology and metabolism • 2013
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