Beneficial effects of ondansetron as an adjunct to haloperidol for chronic, treatment-resistant schizophrenia: A double-blind, randomized, placebo-controlled study

@article{Zhang2006BeneficialEO,
  title={Beneficial effects of ondansetron as an adjunct to haloperidol for chronic, treatment-resistant schizophrenia: A double-blind, randomized, placebo-controlled study},
  author={Z. Zhang and W. Kang and Q. Li and Xue-yi Wang and A. Ma},
  journal={Schizophrenia Research},
  year={2006},
  volume={88},
  pages={102-110}
}
  • Z. Zhang, W. Kang, +2 authors A. Ma
  • Published 2006
  • Psychology, Medicine
  • Schizophrenia Research
  • BACKGROUND Previous studies suggest that the serotonin-3 (5-HT3) receptor antagonist ondansetron possesses the therapeutic potential for schizophrenia. This study was designed to determine whether ondansetron as an adjunct to haloperidol could enhance the clinical efficacy and reduce the adverse side effects in chronic treatment-resistant schizophrenia. METHODS Under double-blind, randomized conditions, 121 treatment-resistant inpatients with chronic DSM-IV-diagnosed schizophrenia received… CONTINUE READING
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