Beneficial effects of modest systemic hypothermia on locomotor function and histopathological damage following contusion-induced spinal cord injury in rats.

@article{Yu2000BeneficialEO,
  title={Beneficial effects of modest systemic hypothermia on locomotor function and histopathological damage following contusion-induced spinal cord injury in rats.},
  author={Cuijan Yu and Olga Lidia Jimenez and A Marcillo and B Weider and Keith Bangerter and W. Dalton Dietrich and Sandra Milena Barrera Castro and Robert Yezierski},
  journal={Journal of neurosurgery},
  year={2000},
  volume={93 1 Suppl},
  pages={85-93}
}
OBJECT Local spinal cord cooling (LSCC) is associated with beneficial effects when applied following ischemic or traumatic spinal cord injury (SCI). However, the clinical application of LSCC is associated with many technical difficulties such as the requirement of special cooling devices, emergency surgery, and complicated postoperative management. If hypothermia is to be considered for future application in the treatment of SCI, alternative approaches must be developed. The objectives of the… CONTINUE READING