Beneficial effects of intracoronary adenosine as an adjunct to primary angioplasty in acute myocardial infarction.

@article{Marzilli2000BeneficialEO,
  title={Beneficial effects of intracoronary adenosine as an adjunct to primary angioplasty in acute myocardial infarction.},
  author={Mario Marzilli and Emil Orsini and Paolo Marraccini and Roberta Testa},
  journal={Circulation},
  year={2000},
  volume={101 18},
  pages={2154-9}
}
BACKGROUND The benefits of vessel recanalization in acute myocardial infarction (AMI) are limited by reperfusion damage. In animal models, adenosine limits reperfusion injury, reducing infarct size and improving ventricular function. The aim of this study was to evaluate the safety and feasibility of adenosine adjunct to primary PTCA in AMI. METHODS AND RESULTS Fifty-four AMI patients undergoing primary PTCA were randomized to intracoronary adenosine or saline. The 2 groups were similar for… CONTINUE READING
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parison of primary coronary angioplasty and intravenous thrombolytic therapy for acute myocardial infarction : a quantitative review

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