Beneficial effects of hydralazine in severe mitral regurgitation.


The severity of mitral regurgitation is, in part, determined by aortic impedance to left ventricular outflow. Sodium nitroprusside acutely decreases regurgitant flow, but the importance of its dual vasodilating effects, the lowering of peripheral vascular resistance and increasing of venous capacitance, is unclear. We studied the hemodynamic response to… (More)


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@article{Greenberg1978BeneficialEO, title={Beneficial effects of hydralazine in severe mitral regurgitation.}, author={Barry H. Greenberg and Barry M. Massie and Bruce H. Brundage and Elias H. Botvinick and William W. Parmley and Kanu Chatterjee}, journal={Circulation}, year={1978}, volume={58 2}, pages={273-9} }