Beneficial effects of curcumin on hyperlipidemia and insulin resistance in high-fat-fed hamsters.

  title={Beneficial effects of curcumin on hyperlipidemia and insulin resistance in high-fat-fed hamsters.},
  author={Eun-Mi Jang and M P Choi and Un Ju Jung and Myung-Joo Kim and Hye-Jin Kim and S M Jeon and Su-kyung Shin and C S Seong and M. Lee},
  journal={Metabolism: clinical and experimental},
  volume={57 11},
This study investigated the effect of curcumin (0.05-g/100-g diet) supplementation on a high-fat diet (10% coconut oil, 0.2% cholesterol, wt/wt) fed to hamsters, one of the rodent species that are most closely related to humans in lipid metabolism. Curcumin significantly lowered the levels of free fatty acid, total cholesterol, triglyceride, and leptin and the homeostasis model assessment of insulin resistance index, whereas it elevated the levels of high-density lipoprotein cholesterol and… CONTINUE READING


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