Beneficial effects of cannabinoids (CB) in a murine model of allergen-induced airway inflammation: role of CB1/CB2 receptors.

@article{Braun2011BeneficialEO,
  title={Beneficial effects of cannabinoids (CB) in a murine model of allergen-induced airway inflammation: role of CB1/CB2 receptors.},
  author={Andrea Braun and Tabea Engel and Juan Antonio Aguilar-Pimentel and Andreas David Zimmer and Thilo Jakob and Heidrun Behrendt and Martin Mempel},
  journal={Immunobiology},
  year={2011},
  volume={216 4},
  pages={466-76}
}
The endocannabinoid system (ECS) consists of two cannabinoid (CB) receptors, namely CB(1) and CB(2) receptor, and their endogenous (endocannabinoids) and exogenous (cannabinoids, e.g. delta-9-tetrahydrocannabinol (THC)) ligands which bind to these receptors. Based on studies suggesting a role of THC and the ECS in inflammation, the objective of this study was to examine their involvement in type I hypersensitivity using a murine model of allergic airway inflammation. THC treatment of C57BL/6… CONTINUE READING
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