Beneficial effects of bradykinin on porcine ischemic myocardium

@article{Tio1991BeneficialEO,
  title={Beneficial effects of bradykinin on porcine ischemic myocardium},
  author={Ren{\'e} Tio and T. J. M. Tob{\'e} and Klaas J. Bel and Cees D.J. De Langen and W. H. van Gilst and Harry Wesseling},
  journal={Basic Research in Cardiology},
  year={1991},
  volume={86},
  pages={107-116}
}
SummaryExogenous bradykinin was administered to pigs in which an experimental infarction was evoked by ischemia and reperfusion. Ischemia (45 min) was induced in a closed-chest model with a balloon catheter in the left anterior descending artery, reperfusion by deflating and removing the balloon. The pigs were treated with saline (n = 11) or bradykinin (0.1 mg/kg in 30 min) infusion (n = 10) during the last 15 min of the ischemic period and the first 15 min of reperfusion.During ischemia, heart… CONTINUE READING

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