Beneficial effects of aggressive low-density lipoprotein cholesterol lowering in women with stable coronary heart disease in the Treating to New Targets (TNT) study.

@article{Wenger2008BeneficialEO,
  title={Beneficial effects of aggressive low-density lipoprotein cholesterol lowering in women with stable coronary heart disease in the Treating to New Targets (TNT) study.},
  author={Nanette K Wenger and Sandra J. Lewis and Francine K. Welty and David M. Herrington and V Garrett Bittner},
  journal={Heart},
  year={2008},
  volume={94 4},
  pages={434-9}
}
OBJECTIVE To examine by secondary analysis of the Treating to New Targets (TNT) study whether the benefits of intensive versus standard levels of lipid lowering are equally applicable to women. METHODS A total of 10 001 patients (1902 women) with stable coronary heart disease (CHD) were randomised to double-blind treatment with atorvastatin 10 or 80 mg/day for a median follow-up of 4.9 years. RESULTS In women and men, intensive treatment with atorvastatin 80 mg significantly reduced the… CONTINUE READING