Beneficial effect of selenium supplementation during murine infection with Trypanosoma cruzi.

@article{Davis1998BeneficialEO,
  title={Beneficial effect of selenium supplementation during murine infection with Trypanosoma cruzi.},
  author={Cheryl D. Davis and Lucy J Brooks and C M Calisi and Brian J. Bennett and Douglas M. McElroy},
  journal={The Journal of parasitology},
  year={1998},
  volume={84 6},
  pages={1274-7}
}
Selenium (Se) has been shown to function as an antioxidant that may enhance immunity during microbial infection. To investigate the effect of elevated levels of Se on the course of experimental Chagas' disease, 5 groups of C3HeB/FeJ mice were infected with 10(3) bloodform trypomastigotes of a Brazil strain of Trypanosoma cruzi while receiving supplements of 0 ppm, 2 ppm, 4 ppm, 8 ppm, or 16 ppm Se as sodium selenate in drinking water. After 64 days of infection, survival ranged from 0 to 60… CONTINUE READING
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