Beneficial effect of methylprednisolone on cardiac myocytes in a rat model of severe brain injury.

@article{Emir2005BeneficialEO,
  title={Beneficial effect of methylprednisolone on cardiac myocytes in a rat model of severe brain injury.},
  author={Mustafa Levent Emir and Kanat Ozişik and Kerim Çağli and Pinar Ozisik and S. I. Tuncer and Vedat Bakuy and Erkan Yildirim and Kam{\'e}r Kilinç and Kamil Gol},
  journal={The Tohoku journal of experimental medicine},
  year={2005},
  volume={207 2},
  pages={119-24}
}
Cardiac injury, occurred after traumatic brain injury (TBI), has been recognized for more than a century. Bcl-2 is a key regulatory component of the mitochondrial cell death pathway, and its overexpression is cytoprotective in many cell types. The therapeutic agents, which induce the expression of bcl-2 protein, might provide a new therapy to prevent… CONTINUE READING