Beneficial effect of intermittent cyclical etidronate therapy in hemiplegic patients following an acute stroke.

@article{Sato2000BeneficialEO,
  title={Beneficial effect of intermittent cyclical etidronate therapy in hemiplegic patients following an acute stroke.},
  author={Yoshihiro Sato and Takeshi Asoh and Masahide Kaji and Kotaro Oizumi},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2000},
  volume={15 12},
  pages={
          2487-94
        }
}
Significant decreases in bone mineral density (BMD) occur on the hemiplegic side in chronic stroke patients, which correlate with the degree of paralysis and hypovitaminosis D. In this double-blind, randomized, and prospective study of 98 patients with hemiplegia involving both an upper and lower extremity (55 males and 53 females; mean age, 71.4 +/- 0.6 years) after an acute stroke, 49 were given etidronate for 56 weeks and 49 received a placebo. The BMD was measured by computed X-ray… CONTINUE READING
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