Beneficial effect of epinephrine infusion on cerebral and myocardial blood flows during CPR.

@article{Koehler1985BeneficialEO,
  title={Beneficial effect of epinephrine infusion on cerebral and myocardial blood flows during CPR.},
  author={Raymond C Koehler and John R. Michael and A D Guerci and Nisha Chandra and Charles L. Schleien and J. Michael Dean and Mark C. Rogers and Myron L. Weisfeldt and Richard J. Traystman},
  journal={Annals of emergency medicine},
  year={1985},
  volume={14 8},
  pages={744-9}
}
It is hypothesized that epinephrine improves the ability to resuscitate the heart through a mechanism thought to be related to the increase in aortic pressure. Our results with epinephrine infusion during CPR are consistent with this hypothesis. Epinephrine selectively increased vascular resistance in noncerebral, noncoronary vascular beds, as indicated by a decrease in microsphere-determined blood flow in these areas. This increased vascular resistance raised aortic pressure during the chest… CONTINUE READING

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