Beneficial effect of donepezil augmentation for the management of comorbid schizophrenia and dementia.

@article{Stryjer2003BeneficialEO,
  title={Beneficial effect of donepezil augmentation for the management of comorbid schizophrenia and dementia.},
  author={Rafael Stryjer and Rael David Strous and Faina Bar and Edith Werber and Ginette Shaked and Yosef Buhiri and Moshe Kotler and Abraham Weizman and Jos{\'e} Martin Rabey},
  journal={Clinical neuropharmacology},
  year={2003},
  volume={26 1},
  pages={12-7}
}
Comorbid schizophrenia and dementia is a common clinical phenomenon; however, management of the coexisting illnesses remains incomplete. Donepezil, a cholinesterase inhibitor, may be beneficial for the management of symptoms of Alzheimer's disease, a disease in which cholinergic pathways in the cerebral cortex and basal forebrain are well known to be compromised. Furthermore, impaired cognition in elderly schizophrenic patients has been observed to be more than two thirds; however, there are no… CONTINUE READING
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