Beneficial effect of candesartan and lisinopril against haloperidol-induced tardive dyskinesia in rat.

@article{Thakur2015BeneficialEO,
  title={Beneficial effect of candesartan and lisinopril against haloperidol-induced tardive dyskinesia in rat.},
  author={Kuldeep Singh Thakur and Atish Kumar Prakash and Rohit Bisht and Puneet Kumar Bansal},
  journal={Journal of the renin-angiotensin-aldosterone system : JRAAS},
  year={2015},
  volume={16 4},
  pages={
          917-29
        }
}
INTRODUCTION Tardive dyskinesia is a serious motor disorder of the orofacial region, resulting from chronic neuroleptic treatment of schizophrenia. Candesartan (AT1 antagonist) and lisinopril (ACE inhibitor) has been reported to possess antioxidant and neuroprotective effects. The present study is designed to investigate the effect of candesartan and lisinopril on haloperidol-induced orofacial dyskinesia and oxidative damage in rats. MATERIALS AND METHODS Tardive dyskinesia was induced by… CONTINUE READING
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