Beneficial Effects of Wheat Gluten Hydrolysate to Extend Lifespan and Induce Stress Resistance in Nematode Caenorhabditis elegans

@article{Zhang2013BeneficialEO,
  title={Beneficial Effects of Wheat Gluten Hydrolysate to Extend Lifespan and Induce Stress Resistance in Nematode Caenorhabditis elegans},
  author={Weiming Zhang and Ting Lv and M. Li and Qiuli Wu and L. Yang and Hui Liu and Da-feng Sun and Lingmei Sun and Ziheng Zhuang and Dayong Wang},
  journal={PLoS ONE},
  year={2013},
  volume={8}
}
Previous studies have showed that wheat gluten hydrolysate (WGH) has the anti-oxidative property. In the present study, we examined the possible safety property of WGH and the beneficial effects of WGH to extend lifespan and induce stress resistance using nematode Caenorhabditis elegans as the in vivo assay system. We found that WGH at concentrations of 0.1–1 mg/mL did not cause lethality, influence development, alter locomotion behavior and brood size, and induce significant intestinal… Expand
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