Beneficial Effects of Fecal Microbiota Transplantation on Ulcerative Colitis in Mice

  title={Beneficial Effects of Fecal Microbiota Transplantation on Ulcerative Colitis in Mice},
  author={Zhihui Tian and Jie Liu and Mengyu Liao and WenJuan Li and Jiaqi Zou and Xinxin Han and Mingjie Kuang and Wanqiu Shen and Haidong Li},
  journal={Digestive Diseases and Sciences},
Ulcerative colitis (UC) is a chronic condition and the most common form of inflammatory bowel disease. The goal of standard treatment is mainly to induce and maintain remission with anti-inflammatory, immunosuppressive agents, and/or colectomy. Fecal microbiota transplantation (FMT) has been used successfully to treat relapsing or refractory Clostridium difficile infection. The alteration of microbiota in mouse models of UC as well as in patients suggested the possibility of treating UC with… CONTINUE READING
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