Beneficial Effect of Interleukin-1 Receptor Antagonist Protein on Spinal Cord Injury Recovery in the Rat

@article{Zong2011BeneficialEO,
  title={Beneficial Effect of Interleukin-1 Receptor Antagonist Protein on Spinal Cord Injury Recovery in the Rat},
  author={Shaohui Zong and Gaofeng Zeng and Bo Wei and Chunxiang Xiong and Yuxi Zhao},
  journal={Inflammation},
  year={2011},
  volume={35},
  pages={520-526}
}
We assessed the effect of treatment with the interleukin-1 receptor antagonist protein (IRAP) on morphological and functional recovery in a rat model of SCI. All sections were processed for immunohistochemistry, hematoxylin–eosin, and Nissl staining. Rats were assessed for hind limb motor function using the Basso, Beattie, and Bresnahan (BBB) hind limb locomotor rating scale and the inclined plane test. At 1, 48, and 72 h after operation, there was a significant increase in neurofilament… CONTINUE READING