Bendamustine: the remedy that came in from the cold.

Abstract

binding properties to histones. Binding of this nonanticoagulant heparin to histones strongly inhibited cytotoxic activity in vitro and translated to impaired inflammation and improved survival in animal models of systemic infection and inflammation. This effect of heparin on histones fits well into the current ideas on the role of histones in the… (More)
DOI: 10.1182/blood-2013-12-539817

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