Benchmarking short sequence mapping tools

  title={Benchmarking short sequence mapping tools},
  author={Ayat Hatem and Doruk Bozdag and Amanda Ewart Toland and {\"U}mit V. Çataly{\"u}rek},
  booktitle={BMC Bioinformatics},
The development of next-generation sequencing instruments has led to the generation of millions of short sequences in a single run. The process of aligning these reads to a reference genome is time consuming and demands the development of fast and accurate alignment tools. However, the current proposed tools make different compromises between the accuracy and the speed of mapping. Moreover, many important aspects are overlooked while comparing the performance of a newly developed tool to the… CONTINUE READING
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