Benchmarking of methods for identification of antimicrobial resistance genes in bacterial whole genome data.

@article{Clausen2016BenchmarkingOM,
  title={Benchmarking of methods for identification of antimicrobial resistance genes in bacterial whole genome data.},
  author={Philip T. L. C. Clausen and Ea Zankari and Frank M Aarestrup and Ole Lund},
  journal={The Journal of antimicrobial chemotherapy},
  year={2016},
  volume={71 9},
  pages={
          2484-8
        }
}
OBJECTIVES Next generation sequencing (NGS) may be an alternative to phenotypic susceptibility testing for surveillance and clinical diagnosis. However, current bioinformatics methods may be associated with false positives and negatives. In this study, a novel mapping method was developed and benchmarked to two different methods in current use for identification of antibiotic resistance genes in bacterial WGS data. METHODS A novel method, KmerResistance, which examines the co-occurrence of k… CONTINUE READING
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