Benchmark dose risk assessment for formaldehyde using airflow modeling and a single-compartment, DNA-protein cross-link dosimetry model to estimate human equivalent doses.

@article{Schlosser2003BenchmarkDR,
  title={Benchmark dose risk assessment for formaldehyde using airflow modeling and a single-compartment, DNA-protein cross-link dosimetry model to estimate human equivalent doses.},
  author={Paul Schlosser and Patrick D. Lilly and Rory B. Conolly and Derek B. Janszen and Julie S Kimbell},
  journal={Risk analysis : an official publication of the Society for Risk Analysis},
  year={2003},
  volume={23 3},
  pages={473-87}
}
Formaldehyde induced squamous-cell carcinomas in the nasal passages of F344 rats in two inhalation bioassays at exposure levels of 6 ppm and above. Increases in rates of cell proliferation were measured by T. M. Monticello and colleagues at exposure levels of 0.7 ppm and above in the same tissues from which tumors arose. A risk assessment for formaldehyde was conducted at the CIIT Centers for Health Research, in collaboration with investigators from Toxicological Excellence in Risk Assessment… CONTINUE READING

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