Bench-to-bedside review: Association of genetic variation with sepsis

@article{Sutherland2009BenchtobedsideRA,
  title={Bench-to-bedside review: Association of genetic variation with sepsis},
  author={Ainsley Sutherland and Keith R. Walley},
  journal={Critical Care},
  year={2009},
  volume={13},
  pages={210 - 210}
}
Susceptibility and response to infectious disease is, in part, heritable. Initial attempts to identify the causal genetic polymorphisms have not been entirely successful because of the complexity of the genetic, epigenetic, and environmental factors that influence susceptibility and response to infectious disease and because of flaws in study design. Potential associations between clinical outcome from sepsis and many inflammatory cytokine gene polymorphisms, innate immunity pathway gene… CONTINUE READING