Bell-shaped relationship between central blood volume and spontaneous baroreflex function.

@article{Saitoh2008BellshapedRB,
  title={Bell-shaped relationship between central blood volume and spontaneous baroreflex function.},
  author={Takashi Saitoh and Yojiro Ogawa and Ken Aoki and Shigeki Shibata and Akira Otsubo and Jitsu Kato and Ken-ichi Iwasaki},
  journal={Autonomic neuroscience : basic & clinical},
  year={2008},
  volume={143 1-2},
  pages={46-52}
}
Spontaneous baroreflex function can be altered by acute changes in central blood volume. Both a reduction in spontaneous baroreflex function at central hypovolemia and augmentation at hypervolemia suggest a dose-effect relationship between central blood volume and spontaneous baroreflex function. However, this relationship has not been quantified over stepwise widespread changes in central blood volume. Twelve individuals underwent central hypovolemia at two levels of lower body negative… CONTINUE READING