Belatacept As an Alternative to Calcineurin Inhibitors in Patients with Solid Organ Transplants

Abstract

The goal of immunosuppression in transplantation has shifted to improving long-term outcomes, reducing drug-induced toxicities while preserving the already excellent short-term outcomes. Long-term gains in solid organ transplantation have been limited at least partly due to the nephrotoxicity and metabolic side effects of calcineurin inhibitors (CNIs). The… (More)
DOI: 10.3389/fmed.2017.00060

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