Beijing ambient particle exposure accelerates atherosclerosis in ApoE knockout mice.

@article{Chen2013BeijingAP,
  title={Beijing ambient particle exposure accelerates atherosclerosis in ApoE knockout mice.},
  author={Tian Jiao Chen and Guang Jia and Yongjie Wei and Jiucun Li},
  journal={Toxicology letters},
  year={2013},
  volume={223 2},
  pages={146-53}
}
BACKGROUND Air pollution is associated with significant adverse health effects including increased cardiovascular morbidity and mortality. However research on the cardiovascular effect of "real-world" exposure to ambient particulate matter (PM) in susceptible animal model is very limited. In this study, we aimed to investigate the association between Beijing ambient particle exposure and the atherosclerosis development in the apolipoprotein E knockout mice (ApoE(-/-) mice). METHODS Two… CONTINUE READING
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