Behcet’s Syndrome

@article{Dalvi2012BehcetsS,
  title={Behcet’s Syndrome},
  author={Sam R Dalvi and Reşit Yıldırım and Yusuf Yazici},
  journal={Drugs},
  year={2012},
  volume={72},
  pages={2223-2241}
}
Behcet’s syndrome (BS) is a vasculitis, seen more commonly around the Mediterranean and the Far East, and manifests with oral and genital ulcerations, skin lesions, uveitis, and vascular, central nervous system and gastrointestinal involvement. Its natural history of getting less severe over time, more severe disease in males and lack of specific diagnostic testing separates it from other commonly seen conditions in rheumatology. Most of the serious manifestations respond well to… 

Immunopathogenesis Of Behçet Disease.

TLDR
A review of the relevant published literature about the immunopathogenesis of Behçet's Disease is presented and several studies have implicated T cells and monocytes in the pathogenesis of BD.

Treatment of Behçet's Disease: An Algorithmic Multidisciplinary Approach

TLDR
A stepwise, symptom-based, algorithmic approach is proposed for the management of Behçet's disease with a holistic perspective to reduce the morbidity and mortality of the disease.

Gr upSM Etiopathogenesis and Immunology of Behçet ’ s Disease

TLDR
It is suggested that the risk of BD development decreases in those migrating to regions where the BD prevalence is lower, and high BD prevalence supports the fact that environmental factors play a role in the disease etiology.

Neutrophilic Dermatosis and Management Strategies for the Inpatient Dermatologist

TLDR
This review provides a structural overview of neutrophilic dermatoses that may present in the inpatient setting along with diagnostic work-up and management strategies.

Immune keratitis: An unusual primary presentation of neuro-Behçet’s disease

TLDR
Detailed systemic examination and laboratory investigations were diagnostic of neuro-Behçet’s disease, and patient responded to systemic steroidal and immunosuppressive therapy characterized by corneal healing and visual acuity improvement to 6/6 and 6/9.

Oral Ulcerative Lesions

TLDR
Recurrent aphthous stomatitis (RAS) is the most frequent ulcerative disorder of the oral cavity, affecting 10–20% of the general population, and its management depends on the frequency and severity of the lesions.

Association of Rho-kinase 1 (ROCK1) Gene Polymorphisms with Behçet’s Disease

TLDR
This is the first study to show that ROCK1 gene polymorphisms may have a significant impact on susceptibility to Behçet’s disease.

Mean Platelet Volume

TLDR
The authors concluded that mean platelet volume (MPV) might be a diagnostic marker of Behçet disease (BD) and recurrent aphthous stomatitis but it could not differentiate these diseases.

The frequency and effect of fibromyalgia in patients with Behçet's disease.

TLDR
It is suggested that patients with Behçet's disease have an increased severity of depression and anxiety, higher frequency of FM, and worsened QoL than healthy individuals.

References

SHOWING 1-10 OF 120 REFERENCES

Behcet’s disease

TLDR
Differential diagnosis excluding Sweet’s disease, pemphigus, erythema nodosum and Crohn's disease is important, and positive laboratory data for pathergy test, prick test for dead Streptococci and HLA-B51 are emphasized to make appropriate diagnosis in these criteria.

Behçet's syndrome and micro-organisms.

The role of streptococcal hypersensitivity in the pathogenesis of Behçet's Disease.

TLDR
The pathogenesis of BD was discussed referring to intrinsic genetic factors and extrinsic triggering factors in aspects of streptococcal hypersensitivity, which might be acquired through the innate immune mechanisms.

A historical review of early descriptions of Adamantiades-Behçet's disease.

Adamantiades-Behcet's disease is a chronic, multisystemic inflam- matory disorder, which is clinically characterized by relapsing oral aphthous and genital ulcers, and ocular vascular lesions

Neuro-behçet’s syndrome: Differential diagnosis and management

Behçet’s syndrome (BS) is a multisystem disease of unknown etiology, characterized by chronic relapsing cardinal symptoms of orogenital ulcers, uveitis, and different skin lesions. Its major

Behçet’s Syndrome

TLDR
Behçet’s syndrome is a systemic vasculitis with an unknown etiology affecting the small and large vessels of the venous and arterial systems and the presence of two clusters of disease expression suggests there may be more than one disease mechanism operative in this complex disorder.

Behcet's Disease with Uveitis in Taiwan

Prognosis in Behçet’s Syndrome

TLDR
Several aspects of morbidity and mortality due to Behcet’s syndrome are reviewed, including the outcome of eye disease is improving significantly after 1990 compared to the era before azathioprine and cyclosporine, and prognosis is still grim for pulmonary artery aneurysms and parenchymal neurological involvement.

Bone mineral density in patients with Behçet’s disease

TLDR
In conclusion, although it is difficult to draw definite conclusions due to the relatively small sample size, this study confirms that bone mineral density in Behçet’s disease was not lower than in healthy subjects.

Cyclosporine for Behçet's uveitis: is it associated with an increased risk of neurological involvement?

TLDR
In patients with Behçet's uveitis, cyclosporine seems to be associated with an increased risk of developing pNBD, although the reason for this is unknown.
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