Behavioural sensitization after repeated exposure to Δ9-tetrahydrocannabinol and cross-sensitization with morphine

  title={Behavioural sensitization after repeated exposure to Δ9-tetrahydrocannabinol and cross-sensitization with morphine},
  author={C. Cadoni and A. Pisanu and M. Solinas and E. Acquas and G. Chiara},
  • C. Cadoni, A. Pisanu, +2 authors G. Chiara
  • Published 2001
  • Psychology, Medicine
  • Psychopharmacology
  • Abstract. Rationale: Repeated exposure to several drugs of abuse has been reported to induce behavioural sensitization. So far no evidence has been provided that such a phenomenon also applies to cannabinoids. Objectives: In this study we investigated if repeated exposure to Δ9-tetrahydrocannabinol (Δ9-THC) induces behavioural sensitization. In addition we tested the possibility of cross-sensitization between Δ9-THC and morphine. Methods: Male Sprague-Dawley rats were administered for 3 days… CONTINUE READING
    158 Citations

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