Behavioural sensitisation following repeated intermittent oral administration of Catha edulis in rats

@article{Banjaw2005BehaviouralSF,
  title={Behavioural sensitisation following repeated intermittent oral administration of Catha edulis in rats},
  author={Mehret Yerdaw Banjaw and Werner H. Schmidt},
  journal={Behavioural Brain Research},
  year={2005},
  volume={156},
  pages={181-189}
}
A prolonged use of psychostimulants has been suggested to induce long-lasting behavioural sensitisation which plays a role in the acquisition and maintenance of addictive behaviour. A study was conducted to evaluate the effect of repeated oral administration of Catha edulis in rats. Male Sprague-Dawley rats divided into five groups received: saline, S-(-)-cathinone (1.5 mg/kg), D-(+)-amphetamine (1.5 mg/kg) and standardized C. edulis extract (50 or 200 mg/kg) once daily for nine consecutive… CONTINUE READING
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