Behavioural genetics of Alzheimer's disease: a comprehensive review

  title={Behavioural genetics of Alzheimer's disease: a comprehensive review},
  author={Marcin Flirski and Tomasz Sobow and Iwona Kloszewska},
  booktitle={Archives of medical science : AMS},
Behavioural and psychological symptoms of dementia (BPSD) are present in the course of the illness in up to 90% of patients with Alzheimer's disease (AD). They are the main source of caregiver burden and one of the major factors contributing to early institutionalization. The involvement of a genetic component in BPSD aetiology seems beyond controversy, though the exact significance of particular polymorphisms is uncertain in the majority of cases. Multiple genes have been assessed for their… CONTINUE READING


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