Behavioural genetics in mood and anxiety: a next step in finding novel pharmacological targets.

@article{Malsen2008BehaviouralGI,
  title={Behavioural genetics in mood and anxiety: a next step in finding novel pharmacological targets.},
  author={Annetrude J G de Mooij-van Malsen and Berend Olivier and Martien J. Kas},
  journal={European journal of pharmacology},
  year={2008},
  volume={585 2-3},
  pages={436-40}
}
The pharmacological treatment of mood and anxiety disorders has for long relied on the serendipitous findings of monoaminergic and benzodiazepine drugs more than 50 years ago. These treatments, however, are therapeutically insufficient and even though more recently developed drugs are particularly improving side effects, the efficacy or response rate of the drugs has fundamentally not improved. Therefore it is necessary to develop new methods to identify novel mechanisms not based on merely the… CONTINUE READING