Behavioural effects of serotonin agonists and antagonists in the rat and marmoset

@article{Elliott1990BehaviouralEO,
  title={Behavioural effects of serotonin agonists and antagonists in the rat and marmoset},
  author={Peter J. Elliott and Dominic M Walsh and S. P. Close and Guy A Higgins and Austin G Hayes},
  journal={Neuropharmacology},
  year={1990},
  volume={29},
  pages={949-956}
}
The present study was conducted to investigate the effects of various 5-hydroxytryptamine (5-HT) agonists and antagonists on motor behaviour in rats and marmosets. Various motor-based responses were assessed after central or peripheral administration of 5-HT agents to rats and marmosets. Drugs acting as agonists at the 5-HT1A receptor (8-OHDPAT, gepirone, BMY-7378, NAN-190, PAPP (LY165163) and flesinoxan) and 5-HT2/1C receptors (DOI) were found to reverse neuroleptic-induced catalepsy in the… CONTINUE READING

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