Behavioural effects in adulthood of neonatal manipulation of brain serotonin levels in normal and androgenized females.

@article{Wilson1992BehaviouralEI,
  title={Behavioural effects in adulthood of neonatal manipulation of brain serotonin levels in normal and androgenized females.},
  author={Catherine A. Wilson and Ivan Gonzalez and Francesca Farabollini},
  journal={Pharmacology, biochemistry, and behavior},
  year={1992},
  volume={41 1},
  pages={91-8}
}
5HT concentrations in the hypothalamus are higher in females than males over the second week of life and this differentiation is testosterone-dependent. We have investigated the possible influence of 5HT over this period on the development of systems that control adult behaviour, in particular those influenced by neonatal testosterone. Neonatal androgenization (250 micrograms/pup testosterone propionate; TP; on day 1 postpartum) induced a masculine pattern of behaviour in females ovariectomised… CONTINUE READING