Behavioural and pharmacological characterisation of the elevated “zero-maze” as an animal model of anxiety

@article{Shepherd1994BehaviouralAP,
  title={Behavioural and pharmacological characterisation of the elevated “zero-maze” as an animal model of anxiety},
  author={Jon K. Shepherd and Savraj S. Grewal and Allan Fletcher and David J. Bill and Colin Trevor Dourish},
  journal={Psychopharmacology},
  year={1994},
  volume={116},
  pages={56-64}
}
The elevated “zero-maze” is a modification of the elevated plus-maze model of anxiety in rats which incorporates both traditional and novel ethological measures in the analysis of drug effects. The novel design comprises an elevated annular platform with two opposite enclosed quadrants and two open, removing any ambiguity in interpretation of time spent on… CONTINUE READING