Behavioural and neurochemical consequences of chronic gut microbiota depletion during adulthood in the rat.

Abstract

Gut microbiota colonization is a key event for host physiology that occurs early in life. Disruption of this process leads to altered brain development which ultimately manifests as changes in brain function and behaviour in adulthood. Studies using germ-free (GF) mice highlight the extreme impact on brain health that results from life without commensal… (More)
DOI: 10.1016/j.neuroscience.2016.10.003

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Cite this paper

@article{Hoban2016BehaviouralAN, title={Behavioural and neurochemical consequences of chronic gut microbiota depletion during adulthood in the rat.}, author={Angela Hoban and Rachel D. Moloney and Anna V. Golubeva and K-A McVey Neufeld and Orla O'Sullivan and E. A. Patterson and Catherine Stanton and Ted G Dinan and Geraldine H Clarke and John F Cryan}, journal={Neuroscience}, year={2016}, volume={339}, pages={463-477} }