Behavioural and electroencephalographic interactions between haloperidol and PCP/sigma ligands in the rat

@article{Sagratella2005BehaviouralAE,
  title={Behavioural and electroencephalographic interactions between haloperidol and PCP/sigma ligands in the rat},
  author={Simone Sagratella and Antonella De Carolis and Antonella P{\'e}zzola and Patrizia Popoli},
  journal={Psychopharmacology},
  year={2005},
  volume={105},
  pages={485-491}
}
Phencyclidine (PCP) and sigma ligands produce a typical excitatory behaviour in rats, characterized by circling and head- and body-weaving. Excitatory amino acid antagonists such as 2-amino 5-phosphonovaleric acid (AP5) or 3-(±)-2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP) also produce a PCP-like excitatory behaviour in rats. In the present paper… CONTINUE READING