Behavioural and developmental toxicity of chlorpyrifos and nickel chloride to zebrafish (Danio rerio) embryos and larvae.

@article{Kienle2009BehaviouralAD,
  title={Behavioural and developmental toxicity of chlorpyrifos and nickel chloride to zebrafish (Danio rerio) embryos and larvae.},
  author={Cornelia Kienle and Heinz-R K{\"o}hler and Almut Gerhardt},
  journal={Ecotoxicology and environmental safety},
  year={2009},
  volume={72 6},
  pages={
          1740-7
        }
}
In order to assess the combined toxicity of environmental chemicals with different modes of action in acute (2 h) and subchronic (11 d) exposures, embryos and larvae of Danio rerio were exposed to a heavy metal salt, nickel chloride (NiCl2), the insecticide chlorpyrifos (CHP) and their binary mixtures. Chlorpyrifos is an acetylcholine esterase inhibitor, which is likely to affect behaviour of the organism. NiCl2 targets the active sites of enzymes and is regarded as an unspecific toxicant for… Expand
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