Behaviour of urinary D-glucaric acid excretion in surgical patients and anaesthesiology staff acutely exposed to isoflurane and nitrous oxide.

@article{Franco1991BehaviourOU,
  title={Behaviour of urinary D-glucaric acid excretion in surgical patients and anaesthesiology staff acutely exposed to isoflurane and nitrous oxide.},
  author={Giuliano Franco and Paolo Marraccini and Gaia Santagostino and P Filisetti and Ivano Preseglio},
  journal={La Medicina del lavoro},
  year={1991},
  volume={82 6},
  pages={527-32}
}
Liver function abnormalities have been observed in humans exposed to anaesthetics inhalation. Furthermore, experimental studies have revealed changes in microsomal enzyme activity caused by inhalation of a variety of anaesthetics. The study was designed to assess liver microsomal enzyme function by means of a simple non-invasive test, i.e., measurement of urinary D-glucaric acid (UDGA) excretion. Three groups of selected subjects were examined: (i) 20 patients undergoing orthopaedic surgery… CONTINUE READING