Behavioral suppression induced by cannabinoids is due to activation of the arachidonic acid cascade in rats

@article{Yamaguchi2001BehavioralSI,
  title={Behavioral suppression induced by cannabinoids is due to activation of the arachidonic acid cascade in rats},
  author={T. Yamaguchi and Y. Shoyama and S. Watanabe and T. Yamamoto},
  journal={Brain Research},
  year={2001},
  volume={889},
  pages={149-154}
}
  • T. Yamaguchi, Y. Shoyama, +1 author T. Yamamoto
  • Published 2001
  • Medicine, Biology
  • Brain Research
    • Tetrahydrocannabinol (THC) is the principle psychoactive ingredient of marijuana and produces various psychoactive effects through the brain cannabinoid (CB1) receptor. The CB1 receptor belongs to the seven-transmembrane domain family of G-protein-coupled receptors and is involved in the arachidonic acid cascade in the brain. Few reports have attempted to clarify the functional role of endogenous cannabinoid and the arachidonic acid cascade through the CB1 receptor using a behavioral paradigm… CONTINUE READING
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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 34 REFERENCES
    Molecular characterization of a peripheral receptor for cannabinoids
    3981
    Delta 9-tetrahydrocannabinol increases arachidonic acid levels in guinea pig cerebral cortex slices.
    23
    Effects of cannabinoids on the activities of mouse brain lipases
    24
    Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    4037
    Delta-9-tetrahydrocannabinol (THC) increases brain prostaglandins in the rat
    22
    2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain.
    1808
    Nonclassical cannabinoid analgetics inhibit adenylate cyclase: development of a cannabinoid receptor model.
    184
    Receptor mediation in cannabinoid stimulated arachidonic acid mobilization and anandamide synthesis.
    78
    Effects of a cannabinoid on spontaneous and evoked neuronal activity in the substantia nigra pars reticulata.
    81
    Motor disturbances induced by an acute dose of Δ9-tetrahydrocannabinol: Possible involvement of nigrostriatal dopaminergic alterations
    58