Behavioral procedures for evaluating the relative abuse potential of CNS drugs in primates.

@article{Brady1976BehavioralPF,
  title={Behavioral procedures for evaluating the relative abuse potential of CNS drugs in primates.},
  author={Joseph V. Brady and R R Griffiths},
  journal={Federation proceedings},
  year={1976},
  volume={35 11},
  pages={
          2245-53
        }
}
Laboratory animal drug self-administration procedures for evaluating pharmacological abuse potential have focused on performance measurements involving relative rates of drug-maintained responding, discrete-trial choice determinations, and response cost or progressive ratio values. Relative rate measures have proved historically difficult to use for reliable reinforcement strength determinations. Discrete-trial choice procedures for assessing the relative reinforcing properties of stimulus… CONTINUE READING

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