Behavioral mechanisms underlying nicotine reinforcement.

  title={Behavioral mechanisms underlying nicotine reinforcement.},
  author={Laura E Rupprecht and Tracy T Smith and Rachel L. Schassburger and Deanne M. Buffalari and Alan F. Sved and Eric C. Donny},
  journal={Current topics in behavioral neurosciences},
Cigarette smoking is the leading cause of preventable deaths worldwide, and nicotine, the primary psychoactive constituent in tobacco, drives sustained use. The behavioral actions of nicotine are complex and extend well beyond the actions of the drug as a primary reinforcer. Stimuli that are consistently paired with nicotine can, through associative learning, take on reinforcing properties as conditioned stimuli. These conditioned stimuli can then impact the rate and probability of behavior and… CONTINUE READING