Behavioral, electrophysiological and histopathological consequences of systemic manganese administration in MEMRI.

Abstract

Manganese (Mn(2+))-enhanced magnetic resonance imaging (MEMRI) offers the possibility to generate longitudinal maps of brain activity in unrestrained and behaving animals. However, Mn(2+) is a metabolic toxin and a competitive inhibitor for Ca(2+), and therefore, a yet unsolved question in MEMRI studies is whether the concentrations of metal ion used may… (More)
DOI: 10.1016/j.mri.2009.12.022

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@article{Eschenko2010BehavioralEA, title={Behavioral, electrophysiological and histopathological consequences of systemic manganese administration in MEMRI.}, author={Oxana Eschenko and Santiago Canals and I. Simanova and Nikos K. Logothetis}, journal={Magnetic resonance imaging}, year={2010}, volume={28 8}, pages={1165-74} }