Behavioral effects of four novel synthetic cathinone analogs in rodents

  title={Behavioral effects of four novel synthetic cathinone analogs in rodents},
  author={Michael B. Gatch and Ritu A Shetty and Nathalie Sumien and Michael J Forster},
  journal={Addiction Biology},
A new generation of novel cathinone compounds has been developed as stimulant substitutes to avoid drug control laws and detection of use by blood tests. Dipentylone, N‐ethylhexedrone, 4‐chloroethcathinone (4‐CEC), and 4′‐methyl‐α‐pyrrolidinohexiophenone (MPHP) were tested for in vivo psychostimulant‐like effects to assess their abuse liability. Locomotor activity was assessed in an open‐field assay using Swiss–Webster mice to screen for locomotor stimulant effects and to identify behaviorally… 
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Human Neuronal Cell Lines as An In Vitro Toxicological Tool for the Evaluation of Novel Psychoactive Substances
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Locomotor activity and discriminative stimulus effects of a novel series of synthetic cathinone analogs in mice and rats
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Locomotor stimulant and discriminative stimulus effects of ‘bath salt’ cathinones
Several commonly marketed cathinones produce discriminative stimulus effects comparable with those of cocaine and methamphetamine, which suggests that these compounds are likely to have similar abuse liabilities.
Behavioral evidence for the abuse potential of the novel synthetic cathinone alpha-pyrrolidinopentiothiophenone (PVT) in rodents
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The inference that second generation cathinones pentylone and pentedrone have abuse liability greater than that of methylone is supported.
Discriminative stimulus and locomotor effects of para-substituted and benzofuran analogs of amphetamine.
Effects of D1 and D2 receptor antagonists on the discriminative stimulus effects of methylendioxypyrovalerone and mephedrone in male Sprague-Dawley rats trained to discriminate D-amphetamine
Preliminary findings indicate that MDPV and MEPH produce interoceptive stimuli that are similar to those produced by AMPH and that D1 and D2 dopamine receptors contribute to these effects.
Cocaine-like discriminative stimulus effects of amphetamine, cathinone, methamphetamine, and their 3,4-methylenedioxy analogs in male rhesus monkeys
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