Behavioral effects of four novel synthetic cathinone analogs in rodents

@article{Gatch2020BehavioralEO,
  title={Behavioral effects of four novel synthetic cathinone analogs in rodents},
  author={Michael B. Gatch and Ritu A Shetty and Nathalie Sumien and Michael J Forster},
  journal={Addiction Biology},
  year={2020},
  volume={26}
}
A new generation of novel cathinone compounds has been developed as stimulant substitutes to avoid drug control laws and detection of use by blood tests. Dipentylone, N‐ethylhexedrone, 4‐chloroethcathinone (4‐CEC), and 4′‐methyl‐α‐pyrrolidinohexiophenone (MPHP) were tested for in vivo psychostimulant‐like effects to assess their abuse liability. Locomotor activity was assessed in an open‐field assay using Swiss–Webster mice to screen for locomotor stimulant effects and to identify behaviorally… 

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