Behavioral effects of cocaine and dopaminergic strategies for preclinical medication development

@article{Platt2002BehavioralEO,
  title={Behavioral effects of cocaine and dopaminergic strategies for preclinical medication development},
  author={Donna M. Platt and James K. Rowlett and Roger D. Spealman},
  journal={Psychopharmacology},
  year={2002},
  volume={163},
  pages={265-282}
}
Abstract Rationale. The illicit use of cocaine is a persistent health problem worldwide. Currently, there are no broadly effective pharmacotherapies to treat cocaine addiction. A prerequisite for development of useful anti-cocaine medications is an understanding of the pharmacological basis of cocaine's effects. The functional analysis of behavior in laboratory animals has allowed for the development of strategies identifying candidate medications to treat cocaine addiction. Objectives. This… CONTINUE READING