Behavioral economics of food reinforcement and the effects of prefeeding, extinction, and eticlopride in dopamine D2 receptor mutant mice

@article{Soto2011BehavioralEO,
  title={Behavioral economics of food reinforcement and the effects of prefeeding, extinction, and eticlopride in dopamine D2 receptor mutant mice},
  author={Paul L. Soto and David K. Grandy and Steven R. Hursh and Jonathan Katz},
  journal={Psychopharmacology},
  year={2011},
  volume={215},
  pages={775-784}
}
Several studies have investigated the reinforcing effects of food in genetically engineered mice lacking dopamine D2 receptors (DA D2Rs); however, behavioral economic analyses quantifying reinforcement have not been conducted. The role of DA D2Rs in food reinforcement was examined by comparing responding under various fixed-ratio (FR) schedules of reinforcement, and effects of extinction, satiation, and the DA D2R antagonist eticlopride, in mice with and without genetic deletions of the… CONTINUE READING

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Statistical method in biological assay, 2nd ed

  • DJ Finney
  • 1964
Highly Influential
2 Excerpts

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