Behavioral disinhibition requires dopamine receptor activation

  title={Behavioral disinhibition requires dopamine receptor activation},
  author={Marcel M. van Gaalen and Reinhild J. Brueggeman and Patricia F. C. Bronius and Anton N M Schoffelmeer and Louk J. M. J. Vanderschuren},
Behavioral disinhibition is a manifestation of impulsive behavior that is prominent in the psychopathology of various psychiatric disorders, but the underlying neural mechanisms are unclear. Behavioral disinhibition can be investigated by measuring premature responding in the 5-choice serial reaction time task (5-CSRTT) in which attentional parameters can be measured as well. The objective of the study was to investigate the involvement of dopamine neurotransmission in behavioral disinhibition… CONTINUE READING
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