Behavioral deficits induced by third-trimester equivalent alcohol exposure in male C57BL/6J mice are not associated with reduced adult hippocampal neurogenesis but are still rescued with voluntary exercise.

@article{Hamilton2016BehavioralDI,
  title={Behavioral deficits induced by third-trimester equivalent alcohol exposure in male C57BL/6J mice are not associated with reduced adult hippocampal neurogenesis but are still rescued with voluntary exercise.},
  author={Gilian F Hamilton and Paula J Bucko and Daniel S Miller and R S Deangelis and Claire Krebs and Justin S Rhodes},
  journal={Behavioural brain research},
  year={2016},
  volume={314},
  pages={96-105}
}
Prenatal alcohol exposure can produce permanent alterations in brain structure and profound behavioral deficits. Mouse models can help discover mechanisms and identify potentially useful interventions. This study examined long-term influences of either a single or repeated alcohol exposure during the third-trimester equivalent on survival of new neurons in the hippocampus, behavioral performance on the Passive avoidance and Rotarod tasks, and the potential role of exercise as a therapeutic… CONTINUE READING
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