Behavioral conditioning of lipopolysaccharide-induced anorexia

@article{Exton1995BehavioralCO,
  title={Behavioral conditioning of lipopolysaccharide-induced anorexia},
  author={Michael S. Exton and Diane F. Bull and Maurice G. King},
  journal={Physiology \& Behavior},
  year={1995},
  volume={57},
  pages={401-405}
}
View on Elsevier
doi.org
34 Citations
Highly Influential Citations
3
Background Citations
11
Methods Citations
1

34 Citations

Citation Type

Citation Type

Behaviorally conditioned anorexia: Role of gastric emptying and prostaglandins
Pavlovian conditioning of endotoxin-tolerance in rats
Paradoxical conditioning of the plasma copper and corticosterone responses to bacterial endotoxin
Modification of body temperature and sleep state using behavioral conditioning
Conditioned place aversion with interleukin-1β in mice is not associated with activation of the cytokine network
Central Blockade of IL-1 Does Not Impair Taste-LPS Associative Learning
TLDR
The data show that animals which did not experience a fever response during association phase (due to the LPS encounter) were unable to elicit hyperthermia as part of the conditioned response, indicating that pairing a relevant taste stimulus with an immune challenge might result in the formation of multiple engrams.
Single-trial conditioning in a human taste-endotoxin paradigm induces conditioned odor aversion but not cytokine responses
Conditioned taste aversion with lipopolysaccharide and peptidoglycan does not activate cytokine gene expression in the spleen and hypothalamus of mice
Brief communication Weaken taste-LPS association during endotoxin tolerance
TLDR
Findings indicate that an identical immune challenge can result in completely different neuro-behavioral consequences depending on the immune history of the individual, thus revealing part of the complex interconnection between the immune and neuro-endocrine systems in regulating food selection and consumption during the infectious process.
Weaken taste-LPS association during endotoxin tolerance
...
1
2
3
4
...

References

SHOWING 1-10 OF 42 REFERENCES
Acute-phase immune response: Lipopolysaccharide-induced fever and sleep alterations are not simultaneously conditionable in the rat during the inactive (light) phase
Does a learned taste aversion contribute to the anorectic effect of bacterial lipopolysaccharide?
Modification of body temperature and sleep state using behavioral conditioning
Effects of chronic infusion of lipopolysaccharide on food intake and body temperature of the rat
Modulation of body temperature through taste aversion conditioning
Anorexic effects of interleukin 1 in the rat.
TLDR
Control experiments showed that neither loss of IL-1 potency nor failure in the delivery system were responsible for recovery of food intake, consistent with the view that IL- 1 lowers the set point for body weight, but the development of tolerance prevented the full evaluation of this interpretation.
Verapamil and indomethacin attenuate endotoxin-induced anorexia
Indomethacin blocks the anorexic action of interleukin-1.
Interleukin-1-induced anorexia in the rat. Influence of prostaglandins.
TLDR
IL-1 is anorexigenic in the rat, but this is influenced by the structural form of IL-1, the route and chronicity of administration, the source of dietary fat, and the age of the animal.
Sickness behavior as a new target for drug development.
...
1
2
3
4
5
...