Behavioral changes over time in post-traumatic stress disorder: Insights from a rat model of single prolonged stress

@article{Wu2016BehavioralCO,
  title={Behavioral changes over time in post-traumatic stress disorder: Insights from a rat model of single prolonged stress},
  author={Zhuoyun Wu and Qing Tian and Feng Li and Junqiao Gao and Yuehan Song},
  journal={Behavioural Processes},
  year={2016},
  volume={124},
  pages={123-129}
}
Post-traumatic stress disorder (PTSD) is manifested as a persistent mental and emotional condition after potentially life-threatening events. Different animal models of PTSD have been developed for neuro-pathophysiology and pharmacological evaluations. A single prolonged stress (SPS) induced animal model has demonstrated to result in specific neuro-endocrinological dysregulation, and behavior abnormalities observed in PTSD. However, animal studies of PTSD have mostly been performed at one time… CONTINUE READING
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